Tapping the potential for health research in developing countries.

Those of us who have long been involved in research concerning health problems in developing countries can look back with a sense of satisfaction on the progress made. Advocacy efforts have put the issue on the global agenda; we need to continue to advocate for increased investment and for further strengthening of the capacity that already exists in many developing countries. At the same time, the existing potential should be thoroughly tapped. A number of middle-income developing countries are already making significant investments in science and are contributing to the global knowledge pool. Public funding for health research in developing countries, as a whole, has been estimated by the Global Forum for Health Research to be at least US$ 2.5 billion in 1998 (1). Although this accounts for only 3% of the estimated global funding for health research and development, it is not insignificant. The UNESCO Institute of Statistics estimates that 27% of the total researchers in the world are in developing countries (2). If some developing countries are able to make the research investment to develop armaments, they could certainly make the much smaller commitment for health research. According to the International Federation of Pharmaceutical Manufacturers Associations (3), some developing countries are considered strong candidates for increased biopharmaceutical research and development, on the basis of an assessment of availability of scientists, quality of scientific research institutions, and technological sophistication. These include Argentina, Brazil, Chile, China, eastern European countries, India, South Africa and Thailand. Some ways of enhancing the productivity and impact of the health research community in developing countries may necessitate large investments, and they are worth it. Other ways are feasible with only a relatively small investment. The potential of developing